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You'll also be advised to quit smoking and to avoid trauma to the skin as much as possible.Xeglyze (abametapir) is a pediculicide indicated for the topical treatment of...Even with successful treatment of the underlying Graves' disease, you may still have cosmetic issues and have a hard time getting shoes to fit well.Graves' dermopathy results from a buildup of certain carbohydrates in the skin — the cause of which isn't known. Advertising revenue supports our not-for-profit mission. Other symptoms you may have include: The patches are usually slightly scaly. In the absence of such history, or laboratory confirmation of thyroid autoimmunity [TA], one should consider other disorders in the differential diagnosis. The texture of the affected skin may be similar to that of an orange peel. It often occurs on the shins and on the tops of the feet.Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.Mayo Clinic does not endorse companies or products. The vast majority of people who develop Graves' dermopathy also have Graves' ophthalmopathy. Carbohydrate buildup also causes the eye problems associated with Graves' disease. It is a rare complication of Graves' disease with an incidence rate of about 1 to 5 percent in patients. Dermopathy of Graves’ disease (pretibial myxedema) is an uncommon autoimmune extrathyroidal manifestation of Graves’ disease, seen in 0.5–4.3% of cases as per literature from white Caucasians.

It is usually bilateral, but monolateral variants can be observed.

Diabetic Dermopathy Symptoms. Although a number of disorders may result in hyperthyroidism, Graves' disease is a common cause.Because thyroid hormones affect a number of different body systems, signs and symptoms associated with Graves' disease can be wide ranging and significantly influence your overall well-being. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). This is a common skin condition that is found in diabetic people on their lower legs. Although Graves' disease may affect anyone, it's more common among women and before t… Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations.Milder cases of Graves' dermopathy often improve over time without treatment. This results from a buildup of protein in the skin. As for Graves’ orbitopathy, the most common extrathyroidal manifestation of GD, the pathogenesis is believed to reflect autoimmunity against antigens constitutively expressed by the thyroid and by the extrathyroidal affected tissues. The vast majority of people who develop Graves' dermopathy also have Graves' ophthalmopathy. Graves' disease can run in families. Milder cases of Graves' dermopathy often improve over time without treatment. Initially diabetic dermopathy will appear as patches that range in color from tan to dark brown or pink to red. It is characterized by localized thickening of the skin (1, 2).Commonly localized in the pretibial area, it is therefore often referred to as pretibial myxedema (PTM).