The methods and exercises are coordinated with the lectures and students are expected to understand underlying assumptions and limitations and the basic calculations performed by these computer programs. Prerequisites: graduate standing or permission of the instructor. The Physiology and Microscopic Anatomy courses are closely coordinated within the same schedule. Generally a topic for the semester helps focus the group; past topics have included Synapses and Disease, Neurotransmitter Transporters, Glutamate Receptors, Dendrites, GABA receptors. May be taken for a letter grade or Credit/No Credit. Prerequisites: Nucleic Acids. A major in biology can prepare you PhD, University of California, Berkeley, Kenneth M. Olsen Finally, students conduct individual research projects on a science topic that affects current legislative efforts, either state or national. This course is an advanced graduate course that explores all aspects of DNA damage and the cellular responses to DNA damage. Many of us in different labs, departments, and institutions around STL are actively investigating aspects and effects of climate change; this reading group provides a venue for interacting with others in the community. This course is also for those that want to know more about where their food comes from, how these amazing creatures survive and flourish, and how GMO crops are engineered. Students whoi complete Biol 2010 understand key science concepts, how discoveries lead to applications addressing global challenges, how to effectively use a variety of resources to explore connections between science and biotech business, how to synthesize information from different fields, and how to exhibit strong teamwork skills and communicate information in written and oral forms. L41 Biol 5498 An Introduction to Genomic Analysis. Also required are 6 units of Biol 500 research and an approved thesis from this work, equivalent to the research emphasis described in the preceding paragraph. What: At least once a week there are seminars from researchers in ecology or evolution. L41 Biol 3493 Bacterial Bioprospecting and Biotechnology. BU: SCI. Prerequisites: Biol 2960 and 2970. Fulfills the upper-level laboratory requirement for the biology major. The department also offers a major in environmental biology. Prerequisite: background in physical chemistry, multivariable calculus and basic computer usage. As a biology major in the neuroscience track, you will study the vital processes of all organisms and the environments in which they flourish. radioactive decay, nuclear stability, interactions of radiation with matter) and followed by an overview of how radiochemistry is used in the life sciences. Recent research in the Kunkel lab has revealed that the plant hormone auxin promotes disease development in interactions between P. syringae strain PtoDC3000 and one of its host, Arabidopsis thaliana, a weedy plant in the mustard family. We study the molecular, cellular, and physiological perspectives for each health-related topic, and examine data and methods that support this knowledge. This journal club considers papers from the current literature on chromatin structure and function, with an emphasis on regulation of transcription, epigenetics and genomics. Prerequisite: Basic knowledge of protein structure and function. The material includes molecular, cellular and systems physiology and the relevance of biological timing to ecology and health in everything from protozoans to plants to people. A minimum grade of C- must be earned in each course to count toward the chemistry major. At least 18 units in advanced biology courses (numbered 300 or above) are required. Presentations will be given by students, post-docs and faculty, then discussed. First third of the course focuses on virology, second third on bacteriology and the last third on eukaryotic pathogens. Once registration closes, an email will be sent to those registered to poll for the best days & times. Students arranging to give presentations should consult with one of the faculty organizers at least one week in advance of their talk to gain approval of their topic and the paper chosen. Topics to be covered include: high-throughput sequencing of genetic disorders, x-ray crystallography, and single molecule force spectroscopy by AFM. How does this relate to the binding problem? This course, The Basics of Bio-Entrepreneurship, investigates issues and choices that inventor/scientists encounter when considering the applications and commercialization of early stage scientific discoveries. During the 2020/2021 academic year our research will focus on virulence mechanisms used by the plant pathogen Pseudomonas syringae to promote disease in plants. Prerequisites: Biol 3411 or equivalent; college-level physics, some knowledge of computers.Same as L64 PNP 402, Credit 2 units. Lines of inquiry include environmental isolations, molecular toolbox and host development, plus bioinformatic and laboratory-based analyses of secreted proteins and antibiotics. Recent studies on aging and longevity are now unveiling regulatory mechanisms of the complex biological phenomenon. Bench mentors will be eligible for a travel award to help defray expenses for attending a meeting with their mentee, if that student wins one of the HHMI SURF travel awards (4-5 awarded annually) or is otherwise being supported to present at a scientific meeting. Biologists seek to understand life from prehistoric times, study organisms alive today, and model how life may change in the future. Food, beverages, and music are all part of the mix. Requirements. L41 Biol 5272 Advanced Topics in Immunology. Enrollment is limited to 25 students. Prerequisite, Bio 5068 or permission of coursemasters. Application Instructions. The material found in 2018-2019 Bulletin will probably apply to most interested students. Interdisciplinary Programs. Furthermore, the current onset of "omics" technology and high-throughput biological readouts has opened the possibility of precisely identifying molecular changes and affected metabolic pathways in individual cancers, paving the way for precision medicine and patient care. The course will provide an overview of the history of pharmaceutical research and development activities, with emphasis upon understanding a blend of the scientific, public health, regulatory and business decisions that have shaped the pharmaceutical industry over the past eight decades. Specifically, we will introduce the class to the range of available assay tool kits (detection modalities), and the principles that apply towards assay development, library selection (compound, RNAi) and the translation of benchtop methods to automated platforms. It fulfills the upper-level laboratory requirement for the generic biology major and the biochemistry track; intended for students who have no other courses that fulfill these requirements. The course will be designed to help facilitate the development of such a research plan through didactic work, class presentations, class discussion, and constructive feedback on written work. Minimum 5 students. We will practice how to abstract theories, hypotheses, predictions, mathematically, how to contrast them with data, and interpret the results. Fundamental aspects of the structure, biosynthesis, and function of nucleic acids and the biosynthesis of proteins. The seminars are often followed by receptions which are a chance to get to know each other better and to ask questions. Laboratory work focuses on learning computer-based tools for genome analysis followed by annotation and comparative analysis of the genome of a phage (bacterial virus) that was isolated during the fall semester at Washington University and sequenced over winter break. In-depth exploration of landmark and current papers in genetics, molecular and cell biology, with an emphasis on prokaryotes and eukaryotic microbes. All students are required to complete a set of basic science and mathematics courses. Leveraging the primary research literature, this course examines the history and pathology of infectious disease, the development of antibiotics and vaccines, the rise of antibiotic resistance, and the emergence and reemergence of diseases including Zika virus, Malaria, and Tuberculosis. One hour of paper presentation or research talk and discussion per every two weeks. Prerequisites, Molecular Cell Biology (Bio 5068) and Nucleic Acids (548). We hope that this handbook will be helpful whether you already have chosen or are considering a major in biology. A majority of class time is devoted to active learning through the collection and analysis of data (each lab module lasts 4 weeks). These generally consist of one year of college-level biology, chemistry, mathematics, English and one year of organic chemistry with laboratory. This program serves students from both departments as well as other students from the natural sciences and engineering with an interest in this field. This course examines animal behavior from an evolutionary perspective and explores the relationships between animal behavior, ecology and evolution. In this investigative laboratory course, students will be given high-quality, experimentally determined, three-dimensional structural coordinates, and they will use cutting-edge bioinformatics tools and methods to evaluate and analyze these datasets. The biology major program emphasizes the hierarchical nature of biological complexity and the major structures and functions that emerge at the molecular, cellular, organismal, populational and ecosystem levels. Mastery of this material is evident in a student's ability to critique published data, to identify ambiguities and uncertainties in the conclusions drawn from those data, and to evaluate the societal importance of the research. L41 Biol 5161 Lymphoid Organogenesis: Ontogeny, Inflammation and Cancer. Prerequisite: permission of instructor. Arch: NSM Prerequisite: BIO 5392 Molecular Microbiology & Pathogenesis. Knowledge of anatomy/physiology is optional.Same as E62 BME 5911, L41 Biol 5469 Biochemistry, Biophysics, and Structural Biology Seminar. Nearly 10 years into her teaching career, Daugs found herself back on a university campus this summer in the role of a hands-on learner. As part of this research project, you will complete a simulated job exercise and network with alumni or local leaders in your chosen field, gaining valuable real-world insights and creating essential professional connections. L41 Biol 200S Summer Introduction to Research. In addition to lectures and evaluation of recent clinical and relevant basic immunology literature, an emphasis will be placed on direct encounters with patients and pathologic material when feasible, providing students with a human aspect to discussions of immune pathogenesis. The final part of the course introduces students to concepts of structural biology including protein crystallization, X-ray crystallography and computer modeling of protein structures. Credit 2 units. L41 Biol 5911 Seminar in Biology & Biomedical Sciences. L41 Biol 5484 Genetics and Development of C. elegans Journal Club. Prerequisite, Physical Chemistry, basic Biological Chemistry. Enrollment limited to 16. To complete the BSCS, students must meet all requirements for an applied science degree from the McKelvey School of Engineering in addition to the below requirements. Mechanisms of microevolutionary processes; integrated ecological and genetic approach to study the adaptive nature of the evolutionary process. L41 Biol 404 Laboratory of Neurophysiology. The course is intended primarily for first-year medical students. Biology major requirements must be met with the following courses: Biol 3058, area A (Biol 334, Biol 451, Biol 4810 or Biol 4820), area B , and any course in area C. Students must then choose one of the following laboratory pathways: (1) Laboratory Pathway 1: one of the following courses: Biol 3423, Biol 360, Biol 373W or Biol 404; or (2 . Lecture and discussion cover topics of chromatin and chromosome structure, control of gene transcription, RNA processing, and DNA replication and repair. Is the brain activity that generates consciousness localized or distributed? Students work under the supervision of a mentor in a setting of established, ongoing research. A&S IQ: NSM Review details about forging your path and finding career opportunities in the life sciences, healthcare, and biotechnology fields. Students meet twice during the semester, in week 5 and week 11, for guided discussion of the science in the seminars they attended. Art: NSM When: Most seminars are at 4:00 on Thursdays, though some are on other days. Students who complete this course will be able to ask questions and form hypotheses about the computations and algorithms underlying cognition and behavior, and to design experiments that test these hypotheses. Prerequisites: Psych 100B and one of the following: Psych 354 or 3401 or 344.Same as L33 Psych 374, Credit 3 units. Where appropriate, the class will also emphasize key differences between plants and animals. After successfully completing this detailed 18 hour NOLS Wilderness First Aid course, students are required to write-up a full assessment and treatment plan (5-7 page minimum) for one of the wilderness casualties described in Peter Stark's Last Breath. BU: SCI, L41 Biol 4580 Principles of Human Anatomy and Development, This course will discuss the anatomy of most of the functional systems of the human body. Washington DC 20052. Friday tutorials stress analysis of the primary literature with an emphasis on current research related to material covered in lecture. Facebook; Twitter; Instagram; Snapchat; YouTube Prerequisite: Biol 2970 or permission of instructor. Recent advances regarding the molecular mechanisms responsible for targeting and intercompartmental transport of proteins to and between specific organelles, such as the endoplasmic reticulum, golgi apparatus, lysosomes, mitochondria, and nucleus. A minimum grade of C- is required for all courses to count toward the minor. The regulation of cellular trafficking and the basis of chemokine actions will be covered. Prereqs: one year of general chemistry, one semester of organic chemistry. Topics will be covered in depth over two week blocks and will include glycobiology, lipid homeostasis, protein degradation, and cell senescence. Students enrolled in the course will be required to present one paper and to come prepared to each session, with a question for discussion. Minimum 5 students. Students will learn how to design research workflows, decompose complex problems into simpler solvable units, and apply scientific computing principles to research. Fulfills the upper-level laboratory requirement for the biology major. Biomechanics is the science of understanding the natural world around us in a mechanistic fashion, and it has become a major pillar in investigating the human form and function. 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